A Gulfstream air ambulance operated by Ontario-based Latitude Air Ambulance disappeared early Saturday on a routine medical evacuation flight from Bermuda to Boston, with six people aboard — four crew and two passengers. The FAA alerted the US Coast Guard after losing contact with the Canadian-registered jet, and search assets are now concentrated near Nantucket Island, south of mainland Massachusetts. The flight data tells a stark story. The aircraft departed Bermuda's LF Wade International Airport at 12:41am local time and maintained a cruise altitude of 24,000 feet for much of the journey. Then, in roughly two minutes, the plane descended 13,000 feet before contact was lost entirely. That rate of descent — roughly 6,500 feet per minute — is consistent with a severe in-flight emergency, not a controlled approach. Air traffic control audio captured the final exchange. A controller asked the pilot to confirm he was "coming in blind," and subsequently confirmed the pilot was declaring an emergency. The pilot's own transmissions were not audible in the recording posted by LiveATC.net. The phrase "coming in blind" suggests a potential loss of instruments or visual reference — critical at night over open ocean. Canada's Transport Minister Steven MacKinnon confirmed four Canadians were aboard and said Ottawa is coordinating with US authorities. Bermuda Premier David Burt issued a statement confirming his government is in contact with US authorities and the passengers' families. The NTSB acknowledged the situation Saturday morning but offered no substantive update. The incident exposes a structural reality of aeromedical transport: these are small, specialized operations flying high-performance jets on long overwater routes, often at night, often with critically ill patients aboard. The regulatory and safety frameworks governing air ambulance operators vary significantly between jurisdictions. Latitude Air Ambulance, the registered operator, has not responded to requests for comment. Search and rescue operations in the waters south of Massachusetts face challenging conditions. The Coast Guard has dispatched both air and surface crews, but the search area — open Atlantic between Bermuda and Nantucket — is vast. The gap between the rapid descent data and the total loss of contact leaves investigators with limited information until wreckage or the flight data recorder is located. What happens next depends entirely on what the Coast Guard finds. If the aircraft went into the water at speed, survivability prospects are grim. The NTSB investigation will focus on the descent profile, the pilot's emergency declaration, and whatever maintenance and operational records Latitude Air Ambulance can produce. For now, six families are waiting.