Pope Leo XIV landed in Montevideo on Friday, beginning a 12-day tour of Uruguay, Argentina, and Peru that is equal parts pastoral mission and institutional triage. The 71-year-old pontiff, who underwent surgery to remove a cancerous lung tumour on October 13, told reporters aboard the papal plane he was in "fairly good shape" and had never doubted the trip would proceed. The Vatican said no special medical measures beyond standard papal-trip care were necessary. The choice of itinerary is deliberate. Uruguay is Latin America's most secular country — the least Catholic nation in the region — yet Cardinal Daniel Sturla, archbishop of Montevideo, reported that tickets for papal masses in Paysandu and Florida sold out quickly, with interest extending "well beyond the confines of the Catholic Church." The pope's three-day Uruguay schedule includes a visit to a neighbourhood marked by heavy gang violence, a signal that Leo intends to address structural inequality head-on rather than stage purely ceremonial events. The broader tour functions as a homecoming. Leo served nearly two decades as a missionary in Peru, and the trip will take him to Cusco, the Amazon rainforest, and his old diocese of Chiclayo, where he will privately visit a chapel he helped rebuild. This personal history gives the trip an authenticity that purely diplomatic papal visits lack — Leo has ground-level knowledge of the region's problems, not just briefing-book familiarity. But the strategic context is harder-edged. Latin America has experienced a significant and sustained decline in Catholic affiliation over the past two decades, driven by evangelical Protestantism, secularism, and institutional distrust following abuse scandals. Leo himself acknowledged the stakes, saying he hoped the trip would "strengthen faith, renew hope, and rekindle the fire of charity" in countries facing "rising inequality and violence." This is institution-maintenance language — an acknowledgment that the Vatican's grip on its historically strongest continental base is loosening. The health dimension adds a layer of institutional signalling. By travelling 13 hours from Rome three weeks after cancer surgery, Leo is projecting vitality in an institution that has spent the past decade managing perceptions of papal fragility. Vatican communications chief Maria Montserrat Alvarado pointed to his singing as evidence of lung strength — an oddly specific but effective metric. The subtext: this papacy is not entering a diminished phase. The trip's ambition is notable. Twelve days across three countries, including a visit to the Amazon and a highland city at 3,400 metres elevation, represents one of the most physically demanding papal foreign trips in decades. Whether it translates into measurable institutional renewal or remains a well-received but ephemeral goodwill tour depends on what follows — sustained pastoral investment versus one-off spectacle. The first papal visit to Uruguay since 1988 — a 37-year gap — tells its own story about Vatican attention to the region. Leo is betting that personal presence, biographical connection, and physical stamina can do what institutional infrastructure has not: slow the erosion of Catholic relevance in the continent that still holds the church's largest population base.