David Wilkinson spent the making of his previous documentary, The Marbles — a thoughtful argument for returning the Parthenon sculptures to Greece — quietly battling stage four bowel cancer. That detail, revealed now, reframes everything: 1 in 2 is what happens when a filmmaker stops observing from a safe distance and becomes the subject. The title refers to the statistic that roughly one in two people will develop cancer in their lifetime, but Wilkinson's focus is sharper and more urgent than that. What shocks him — and what drives the film — is the number of young people he encounters in waiting rooms and online bowel cancer communities: people in their 20s, 30s, and 40s who should, by old epidemiological assumptions, not be there at all. Wilkinson is an evangelist in the most literal sense: he has a message, he has personal experience of its stakes, and he is not embarrassed to deliver it directly to camera. The British habit of avoidance and embarrassment around bowel health, he argues plainly, can kill you. Take the test when it arrives in the post. Do not delay. The film functions simultaneously as documentary, personal testimony, and public health appeal. The film's most powerful material comes from its interviews, particularly Milli Tanner — previously profiled by the BBC — whose candour and courage on camera is striking. Her story, like others in the film, involves the specific cruelty of misdiagnosis: symptoms that would trigger urgent investigation in an older patient written off as something else in someone young. Time lost to that assumption costs lives. On the question of why rates are rising in younger cohorts in developed nations, Wilkinson is honest about the limits of current knowledge. Diet and lifestyle are the leading suspects; microplastics are raised as a possibility. There are no clean answers, and the film does not pretend otherwise. What it offers instead is community, witness, and pressure — the kind a filmmaker with a camera and a diagnosis and a platform can actually apply.